叶祥明

◆导师基本情况

1.主任医师，硕士生/博士生导师

2.邮箱：yexmdr@126.com

3.指导专业：康复医学

◆研究领域

1.脑损伤导致的重大中枢神经损伤后的修复的神经影像机制；

2.智能康复技术的研发及应用

◆主讲课程

《康复医学》

◆教育和工作经历

1.教育经历：

1993.09-1996.06浙江中医学院本科

2014/6，台湾荣民总医院，培训学习

2013/8，日本国立康复中心，培训学习

2012/11，华盛顿康复医院学习，培训学习

2.工作经历：

1985/8-至今，浙江省人民医院，康复医学科，住院医师、主治医师、副主任医师、主任医师

◆学术任职

1.中国康复医学会常务理事

2.中国医师协会康复医师分会常务委员

3.中国康复医学会康复治疗专业委员会副主任委员

4.中国康复医学会标准委员会第一届委员会副主任委员

5.中国康复医学会脑血管病专业委员会副主任委员

6.中国康复医学会智能康复专业委员会副主任委员

7.中国康复医学会颅脑创伤专业委员会副主任委员

8.浙江省康复医学会常务副会长兼秘书长（法人代表）

9.浙江省医师协会康复医师分会副会长

◆主持教学科研项目

1.2024年度浙江省重点研发计划“尖兵领雁+X”：基于脑机接口的感知觉、运动增强与康复系统研发及应用研究，2024C03040，负责人；

2.国家重大研发计划：基于脑机接口的脑血管病主动康复技术研究及应用2017YFC1308500，协作单位负责人；

3.浙江省自然科学基金：基于运动想象的脑机接口上肢康复系统对卒中患者大脑可塑性的研究，LGF20H170011，负责人；

4.浙江省自然科学基金：PI3K信号通路在脊髓损伤大鼠并发2型糖尿病中的作用研究，LY15H170002，负责人

◆代表性论著

[1] Yu Cai, Yi Pan, Longcai Liu, Tian Zhang, Chen Liang, Xiaozhou Mou, Xiangming Ye, Wenjun Wang, Xiaochen Dong, Succinct croconic acid-based near-infrared functional materials for biomedical applications, Coordination Chemistry Reviews, doi: 10.1016/j.ccr.2022.214865.（通讯作者：叶祥明 IF：24.833，一区） 

2.Zhang J., Shang D., Ye J., Ling Y., Zhong S., Zhang S., Zhang W., Zhang L., Yu Y., He F., Ye X., Luo B. Altered Coupling Between Cerebral Blood Flow and Voxel-Mirrored Homotopic Connectivity Affects Stroke-Induced Speech Comprehension Deficits [J]. Frontiers in aging neuroscience, 2022, 14: 922154.（通讯作者：叶祥明 IF：5.702）；

3. Mao J., Wang C., Teng C., Wang M., Zhou S., Zhao K., Ye X., Wang Y. Prevalence and Associated Factors of PTSD Symptoms After the COVID-19 Epidemic Outbreak in an Online Survey in China: The Age and Gender Differences Matter [J]. Neuropsychiatric disease and treatment, 2022, 18: 761-71.（通讯作者：叶祥明 IF：2.873）；

4.Zhou Q., Cheng R., Yao L., Ye X., Xu K. Neurofeedback Training of Alpha Relative Power Improves the Performance of Motor Imagery Brain-Computer Interface [J]. Frontiers in human neuroscience, 2022, 16: 831995.（通讯作者：叶祥明 IF：3.473）；

5. Yu Cai, Yi Pan, Longcai Liu, Tian Zhang, Chen Liang, Xiaozhou Mou, Xiangming Ye, Wenjun Wang, Xiaochen Dong, Succinct croconic acid-based near-infrared functional materials for biomedical applications, Coordination Chemistry Reviews, doi: 10.1016/j.ccr.2022.214865.（通讯作者：叶祥明 IF：24.833）；

6. Yang T., Cheng R., Zhang J., Tian L., Sun P., Ye X. Effect of Acupuncture Treatment on Post-stroke Depression by Using Diamond-Like Ultra-Thin Nano-Coating Technology [J]. Cell Mol Biol (Noisy-le-grand), 2022, 68(3): 122-30.（通讯作者：叶祥明 IF：1.206）；

7. Cheng R., Ren W., Luo B., Ye X. Role of purinergic receptors in neural repair and regeneration after spinal cord injury [J]. Neural Regen Res.2022. （通讯作者：叶祥明 IF：6.058）；

8. Sun P., Liu D. G., Ye X. M. Nicotinic Acetylcholine Receptor α7 Subunit Is an Essential Regulator of Seizure Susceptibility [J]. Frontiers in neurology, 2021, 12: 656752.（通讯作者：叶祥明 IF：4.086）； 

9.Ye Qing, Zhang Li, Shao Zhou-Li, Zhang Wei, Li Chao, Ye Xiang-Ming . Two Cu (II)-organic frameworks: Effective CO2 fixation and protective activity on the motor function after stroke by increasing neural stem cells differentiation. Inorganica Chimica Acta [J]. 2020, 512: 119880.（通讯作者：叶祥明 IF：3.118）；

10.Zhang J., Zheng W., Shang D., Chen Y., Zhong S., Ye J., Li L., Yu Y., Zhang L., Cheng R., He F., Wu D., Ye X., Luo B. Fixel-based evidence of microstructural damage in crossing pathways improves language mapping in Post-stroke aphasia [J]. NeuroImage Clinical, 2021, 31: 102774.（通讯作者：叶祥明 IF：4.891）；

11. Zhang J., Zhong S., Zhou L., Yu Y., Tan X., Wu M., Sun P., Zhang W., Li J., Cheng R., Wu Y., Yu Y., Ye X., Luo B. Correlations between Dual-Pathway White Matter Alterations and Language Impairment in Patients with Aphasia: A Systematic Review and Meta-analysis [J]. Neuropsychology review, 2021, 31(3): 402-18.（通讯作者：叶祥明 IF：6.940）；

12. Zhang J., Zhou Z., Li L., Ye J., Shang D., Zhong S., Yao B., Xu C., Yu Y., He F., Ye X., Luo B. Cerebral perfusion mediated by thalamo-cortical functional connectivity in non-dominant thalamus affects naming ability in aphasia [J]. Human brain mapping, 2022, 43(3): 940-54.（通讯作者：叶祥明 IF：5.399）；

13. Ye Qing, Hong L. F., Pan K., Wang Xin, Ye X. M. Study on the Efficacy and Safety of Policosanol in the Treatment of Senile and Elderly Patients with Hyperlipidemia [J]. Indian Journal of Pharmaceutical Sciences, 2021, 83: 77-81. （通讯作者：叶祥明 IF：0.664）； 

14. Cheng R. D., Ren W., Sun P., Tian L., Zhang L., Zhang J., Li J. B., Ye X. M. Spinal cord injury causes insulin resistance associated with PI3K signaling pathway in hypothalamus [J]. Neurochemistry international, 2020, 140: 104839.（通讯作者：叶祥明 IF：4.297）； 

15.Liang F., Chao M., Li J. B., Ye X. M. Characteristics and risk factors of deep vein thrombosis in hemiplegic, healthy and bilateral limbs of hemiplegic patients: a 10-year retrospective study [J]. Journal of thrombosis and thrombolysis, 2021, 51(3): 798-804.（通讯作者：叶祥明 IF：5.221）；

16. Zhang J., Zhong S., Tan T., Li J., Liu S., Cheng R., Tian L., Zhang L., Wang Y., Liu F., Zhou P., Ye X. Comparative Efficacy and Patient-Specific Moderating Factors of Nonsurgical Treatment Strategies for Frozen Shoulder: An Updated Systematic Review and Network Meta-analysis [J]. The American journal of sports medicine, 2021, 49(6): 1669-79.（通讯作者：叶祥明 IF：7.010）； 

17. Zhang J, Tian L, Zhang L, Cheng R, Wei R, He F, Li J, Luo B, Ye XM (通讯作者). Relationship between white matter integrity and post-traumatic cognitive deficits: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry. 2019 Jan;90(1):98-107. （通讯作者：叶祥明 IF：8.263）

18. Cheng R. D., Ren J. J., Zhang Y. Y., Ye X. M. P2X4 receptors expressed on microglial cells in post-ischemic inflammation of brain ischemic injury [J]. Neurochemistry international, 2014, 67: 9-13. （通讯作者：叶祥明 IF：4.297）

19. Li J. B., Cheng R. D., Zhou L., Wen W. S., Zhu G. Y., Tian L., Ye X. M. What drives progressive motor deficits in patients with acute pontine infarction? [J]. Neural regeneration research, 2015, 10(3): 501-4. （通讯作者：叶祥明 IF：6.058）

◆成果奖励

1.外周淋巴水肿的预防与治疗，浙江大学出版社，2022，主编；

2.慢性意识障碍，人民卫生出版社，2022，副主编;

3.传染性疾病呼吸功能康复，浙江大学出版社，2020，主编;

4.关节置换术居家康复指导，电子工业出版社，2019，主编;

5.SPECT脑血流灌注显像技术进行电针“开四关”治疗卒中后抑郁的应用研究，浙江省医药卫生科技成果奖二等奖，2016，叶祥明（1/12）