梁素改

◆ 导师基本情况

精神病与精神卫生学博士，硕士生导师

邮箱：liangsugai@zju.edu.cn

指导专业：精神病与精神卫生学

◆ 研究领域

抑郁症等精神疾病影像遗传学研究

◆ 主讲课程

1. 无

◆ 教育和工作经历

教育经历

2006.09~2011.06 临床医学学士学位  河北医科大学临床学院

2011.09~2014.06 精神病与精神卫生学硕士学位  四川大学

2014.09~2017.06 精神病与精神卫生学博士学位 四川大学

工作经历

2017.07~2021.03 四川大学华西医院 华西心理卫生中心 医师，讲师

2021.03~2021.12 浙江大学医学院附属精神卫生中心（杭州市第七人民医院）主治医师

2021.12~   浙江大学医学院附属精神卫生中心（杭州市第七人民医院），副主任医师

◆ 学术简介

医学博士，硕士研究生导师。2021年入选浙江省医坛新秀。2022年入选杭州市医疗卫生青年拔尖人才。

学术成果交流与展示：

第一作者（包括共同第一）发表SCI 16篇

1. Liang S#, Zhao L#, Ni P, et al. Frontostriatal circuitry and the tryptophan kynurenine pathway in major psychiatric disorders. Psychopharmacology (Berl). 2023 Sep 22. doi: 10.1007/s00213-023-06466-9.

2. Liang S, Cao B, Deng W, et al. Functional dysconnectivity of anterior cingulate subregions in schizophrenia and psychotic and nonpsychotic bipolar disorder. Schizophrenia Research. 2023;254:155-162.

3. Liang, S, Mao, H, Yang, et al. Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study. BMC Psychiatry. 2022;22(1):768.

4. Liang S, Greenshaw AJ, et al. Sleep clinic service model with closed-loop management for insomnia. Asian Journal of Psychiatry. 2022;73:103158. doi: 10.1016/j.ajp.2022.103158.

5. Liang S#, Wu Y#, Hanxiaoran L#, et al. Anhedonia in Depression and Schizophrenia: Brain Reward and Aversion Circuits. Neuropsychiatr Dis Treat. 2022;18:1385-1396.

6. Liang S, Wang Q, Greenshaw AJ, et al. Aberrant triple-network connectivity patterns discriminate biotypes of first-episode medication-naive schizophrenia in two large independent cohorts. Neuropsychopharmacology. 2021; 46(8):1502-1509.

7. Liang S, Deng W, Li X, et al. Biotypes of major depressive disorder neuroimaging evidence from resting-state default mode network patterns. NeuroImage: Clinical. 2020; 28: 102514.

8. Liang S, Li T*. Functional Striatal Abnormalities A Distinct Brain Signature of Schizophrenia. Neuroscience Bulletin. 2021; 37,284–286. doi: 10.1007/s12264-020-00598-0.

9. Liang S#, Li Y#, Zhang Z, et al. Classification of first-episode schizophrenia using multimodal brain features - a combined structural and diffusion imaging study. Schizophrenia Bulletin. 2019; 25; 45(3):591-599.

10. Liang S, Deng W, Li X, et al. Aberrant posterior cingulate connectivity classify first-episode schizophrenia from controls: a machine learning study. Schizophrenia Research. 2020; 220:187-193.

11. Liang S, Brown MRG, Deng W, et al. Convergence and divergence of neurocognitive patterns in schizophrenia and depression. Schizophrenia Research. 2018; 192:327-334.

12. Liang S, Wang Q, Kong X, et al. White matter abnormalities in major depression biotypes identified by diffusion tensor imaging. Neuroscience Bulletin. 2019; 35(5):867-876.

13. Liang S#, Vega R#, Kong X, et al. Neurocognitive graphs of first-episode schizophrenia and major depression based on cognitive features. Neuroscience Bulletin. 2018; 34(2):312-320.

14. Liang S#, Deng W#, Wang Q, et al. Performance of Verbal Fluency as an Endophenotype in Patients with Familial versus Sporadic Schizophrenia and Their Parents. Scientific Reports. 2016; 1;6:32597. doi: 10.1038/srep32597.

15．Liang S#, Yan J#, Zhang T, et al. Differences between non-suicidal self-injury and suicide attempt in Chinese adolescents. Asian Journal of Psychiatry. 2014, 8:76-83.

16. Liang S, et al. Frontostriatal circuitry and the tryptophan kynurenine pathway in major psychiatric disorders. Psychopharmacology (Berl). 2023 Sep 22. doi: 10.1007/s00213-023-06466-9.

主持科研项目：

[1]国家自然科学基金青年基金1项：主持，2019.01-2021.12（结题）

[2]杭州市医药卫生科技项目1项：主持，2021.09-2024.08（在研）

[3]浙江省医药卫生科技计划项目1项：主持，2022.01-2023.12（在研）

◆ 主持教学科研项目

1.无

◆ 授权专利  

1.无